- Omero Antonutti (1 movie)
- Omero Mumba (1 movie)
- Omid Abtahi (1 movie)
- Omid Djalili (3 movies)
- Ona Grauer (2 movies)
- Onira Tares (1 movie)
- Oona Chaplin (2 movies)
- Ophelia Lovibond (4 movies)
- Oprah Winfrey (1 movie)
- Orbert Rogers (1 movie)
- Oreste Baldini (1 movie)
- Orestes Matacena (1 movie)
- Ori Pfeffer (1 movie)
- Orion Lee (1 movie)
- Orion McCabe (2 movies)
- Orlando Bloom (22 movies)
- Orlando Gallegos (1 movie)
- Orlando Jones (1 movie)
- Orly Schuchmacher (1 movie)
- Orphee Sidibe (1 movie)
- Oscar Isaac (4 movies)
- Óscar Jaenada (2 movies)
- Oscar James (1 movie)
- Oscar Kennedy (1 movie)
- Oscar Nunez (1 movie)
- Oscar Wahlberg (1 movie)
- Osheen Jones (1 movie)
- Oskar Bednarek (1 movie)
- Oskar Dawicki (1 movie)
- Oskar Kamiński (1 movie)
- Oskar McNamara (1 movie)
- Oskar Ulvestad (1 movie)
- Osmani Rodriguez (1 movie)
- Osric Chau (1 movie)
- Ossie Davis (1 movie)
- Osy Ikhile (2 movies)
- Ot Palapoo (1 movie)
- Otakuye Conroy (1 movie)
- Ottavio Taddei (1 movie)
- Otto Tausig (1 movie)
- Oussama Kadir (1 movie)
- Owain Arthur (1 movie)
- Owais Ahmed (1 movie)
- Owen Asztalos (1 movie)
- Owen Black (1 movie)
- Owen Finnegan (1 movie)
- Owen Roizman (1 movie)
- Owen Sharpe (1 movie)
- Owen Wilson (6 movies)
- Oz Perkins (1 movie)